Heart attack care: should doctors fix all blockages at once or wait?

NCT ID NCT04968808

First seen Jun 25, 2026 · Last updated Jul 29, 2026 · Updated 5 times

Summary

This study looks at the best timing for opening blocked arteries in people having a certain type of heart attack (NSTEMI) who have multiple blockages. About 1,014 participants will be randomly assigned to have all blockages fixed during the same procedure or to wait a few days between procedures. The goal is to see which approach reduces the chance of death, another heart attack, or needing another procedure within a year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
staged or immediate heart procedure (angioplasty with stents)
What this could lead to
If successful, this could show that doing all heart procedures at once is safer and more effective than waiting days between procedures for NSTEMI patients.
What could go wrong
This is a single-center trial, and results may not apply to all hospitals. The benefit of immediate versus staged procedures may be small, and there is a risk of kidney damage from contrast dye.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chonnam National University Hospital

    RECRUITING

    Gwangju, South Korea

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