Could a simple CO2 test save more lives from septic shock?

NCT ID NCT07179276

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 21 times

Summary

This study tests whether using a measure called the CO2 gap to guide early treatment of septic shock can reduce deaths more than the usual method of tracking lactate levels. Septic shock is a life-threatening condition where blood flow to tissues is poor. The trial will enroll 750 adults in intensive care units with septic shock and compare 28-day death rates between the two approaches.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • APHP Beaujon

    RECRUITING

    Paris, France

    Contact

  • APHP Bicêtre

    RECRUITING

    Paris, France

    Contact

  • APHP La pitié Salpêtrière - Anesthésie et soin intensif

    RECRUITING

    Paris, France

    Contact

  • APHP Lariboisière

    RECRUITING

    Paris, France

    Contact

  • CH Aurillac

    NOT_YET_RECRUITING

    Aurillac, France

    Contact

  • CH Le puy en Velay

    RECRUITING

    Le Puy-en-Velay, France

    Contact

  • CH Moulins-Yzeure

    NOT_YET_RECRUITING

    Moulins, France

    Contact

  • CH Vichy

    NOT_YET_RECRUITING

    Vichy, France

    Contact

  • CH de la Côte Basque

    RECRUITING

    Bayonne, France

    Contact

  • CHRU Strasbourg - Service d'anesthésie-Réanimation médicale

    RECRUITING

    Strasbourg, France

    Contact

  • CHU Bordeaux Hôpital Haut Lévèque

    RECRUITING

    Bordeaux, France

    Contact

  • CHU Bordeaux Pellegrin Hospital

    RECRUITING

    Bordeaux, France

    Contact

  • CHU Clermont-Ferrand Estaing

    RECRUITING

    Clermont-Ferrand, France

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Clermont-Ferrand Gabriel Montpied

    RECRUITING

    Clermont-Ferrand, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU Dijon

    RECRUITING

    Dijon, France

    Contact

  • CHU Grenoble

    NOT_YET_RECRUITING

    Grenoble, France

    Contact

  • CHU Montpellier

    RECRUITING

    Montpellier, France

    Contact

  • CHU Nantes

    RECRUITING

    Nantes, France

    Contact

  • CHU Nîmes

    NOT_YET_RECRUITING

    Nîmes, France

    Contact

  • CHU Poitiers

    RECRUITING

    Poitiers, France

    Contact

  • CHU Rennes

    RECRUITING

    Rennes, France

    Contact

  • CHU Strasbourg Service d'Anesthésie-Réanimation chirurgicale

    RECRUITING

    Strasbourg, France

    Contact

  • CHU la pitié slapêtrière - Anesthésie Réanimation

    RECRUITING

    Paris, France

    Contact

  • CHu Angers

    NOT_YET_RECRUITING

    Angers, France

    Contact

  • Chu Toulouse

    RECRUITING

    Toulouse, France

    Contact

  • HCL - Lyon Sud

    NOT_YET_RECRUITING

    Lyon, France

    Contact

  • HCL Hôpital Edouard Herriot

    NOT_YET_RECRUITING

    Lyon, France

    Contact

Conditions

Explore the condition pages connected to this study.