New combo tackles breast cancer in the liver
NCT ID NCT06860815
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial tests whether combining an immunotherapy drug (cemiplimab) with a radiation treatment (Y90 radioembolization) can help people whose breast cancer has spread to the liver. The treatment aims to boost the immune system to attack tumors while also delivering radiation directly to the liver. The study will enroll 11 adults with stage IV breast cancer that is mainly in the liver.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cemiplimab (immunotherapy drug) and yttrium-90 SIR-Spheres (radioactive microspheres)
What this could lead to
If it works, this could point toward a new combination treatment for breast cancer that has spread to the liver, potentially slowing tumor growth.
What could go wrong
This is a very small pilot study with only 11 participants, so results may not apply to everyone. The combination of immunotherapy and radiation can cause serious side effects, and it is too early to know if it will be effective.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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City of Hope Medical Center
RECRUITINGDuarte, California, 91010, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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