CBD may cut opioid need after knee surgery, new study tests

NCT ID NCT06234631

First seen Feb 21, 2026 · Last updated May 06, 2026 · Updated 10 times

Summary

This study tests whether taking cannabidiol (CBD) before and after knee replacement surgery can lower the amount of opioid painkillers people need. About 380 adults with knee osteoarthritis will receive either CBD or a placebo. The goal is to see if CBD can safely reduce opioid use and improve pain and recovery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Henry Ford Health System

    NOT_YET_RECRUITING

    Detroit, Michigan, 48202, United States

    Contact Phone: •••-•••-••••

    Contact Email: •••••@•••••

    Contact

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.