Immune cells engineered to hunt brain tumors in spinal fluid enter first human test
NCT ID NCT04661384
First seen Feb 21, 2026 · Last updated May 31, 2026 · Updated 20 times
Summary
This early-phase trial tests whether specially engineered immune cells (IL13Rα2-CAR T cells) are safe for adults whose brain cancer (glioblastoma, ependymoma, or medulloblastoma) has spread to the lining of the brain and spinal cord. Ten participants receive these cells to see if they can recognize and attack the tumor. The main goals are to check for side effects and measure overall survival.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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City of Hope Medical Center
Duarte, California, 91010, United States
Conditions
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