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New hope for breast cancer patients with brain metastases

NCT ID NCT05386108

Recruiting now Disease control Sponsor: Stemline Therapeutics, Inc. Source: ClinicalTrials.gov ↗

Summary

This study is testing whether two drugs, elacestrant and abemaciclib, work together to control breast cancer that has spread to the brain. It will involve about 73 adults whose cancer is fueled by estrogen and has spread to the brain. The first part finds the safest dose, and the second part checks how well the combination shrinks tumors in the brain and body.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • A. O. Ospedali Riuniti Parpardo, Piemonte, Messina

    RECRUITING

    Messina, Italy

    Contact

  • AOU Città della Salute e della Scienza di Torino, Ospedale Molinette

    RECRUITING

    Torino, Italy

    Contact

  • AOU Ospedali Riuniti Umberto I-G.M.Lancisi -G.Salesi

    RECRUITING

    Ancona, Italy

    Contact

  • Acibadem Altunizade Hospital

    RECRUITING

    Istanbul, Turkey (Türkiye)

    Contact

  • Adana Sehir Hastanesi

    RECRUITING

    Adana, Turkey (Türkiye)

    Contact

  • Ankara Bilkent Sehir Hastanesi Tibbi Onkoloji Klinigi

    RECRUITING

    Ankara, Turkey (Türkiye)

    Contact

  • Ankara University Medical Faculty

    RECRUITING

    Ankara, Turkey (Türkiye)

    Contact

  • Antwerp University Hospital

    RECRUITING

    Edegem, 2650, Belgium

    Contact

  • Asan Medical Center

    RECRUITING

    Seoul, 05505, South Korea

    Contact

  • Azienda Ospedaliera Santa Maria di Terni

    RECRUITING

    Terni, Italy

    Contact

  • Azienda Ospedaliera Universitaria Federico II

    RECRUITING

    Napoli, Italy

    Contact

  • Azienda Ospedaliero-Universitaria di Modena, Policlinico di Modena

    RECRUITING

    Modena, Italy

    Contact

  • California Research Institute

    RECRUITING

    Los Angeles, California, 90027, United States

    Contact

  • Carle Cancer Center

    RECRUITING

    Urbana, Illinois, 61801, United States

    Contact

  • Centre Francois Baclesse - Oncologie Medicale - Cancerolo

    RECRUITING

    Caen, France

    Contact

  • Centre Hospitalier Universitaire de Poitiers

    RECRUITING

    Poitiers, 86000, France

    Contact

  • Centre Jean Perrin

    RECRUITING

    Clermont-Ferrand, France

    Contact

  • Centre Léon Bérard - Département Oncologie Médicale

    RECRUITING

    Lyon, France

    Contact

  • Centre de Cancerologie du Grand Montpellier

    RECRUITING

    Montpellier, 37070, France

    Contact

  • Clara Campal Comprehensive Cancer Center (CIOCC)

    RECRUITING

    Madrid, Madrid, 28050, Spain

    Contact

  • Clinica Universidad de Navarra

    RECRUITING

    Madrid, Spain

    Contact

  • Clinica Universidad de Navarra

    RECRUITING

    Pamplona, Spain

    Contact

  • Complexo Hospitalario Universitario De Santiago

    RECRUITING

    Santiago de Compostela, 15706, Spain

    Contact

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact

  • Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastirma Hastanesi

    RECRUITING

    Ankara, Turkey (Türkiye)

    Contact

  • EUROMEDICA General Clinic of Thessaloniki

    COMPLETED

    Thessaloniki, 54645, Greece

  • Ege University Medical Faculty

    RECRUITING

    Bornova, Turkey (Türkiye)

    Contact

  • Ewha Womans University MokDong Hospital

    RECRUITING

    Seoul, 07985, South Korea

    Contact

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS

    RECRUITING

    Roma, Italy

    Contact

  • Fundación Instituto Valenciano De Oncología

    RECRUITING

    Valencia, Spain

    Contact

  • Gangnam Severance Hospital

    RECRUITING

    Seoul, 06273, South Korea

    Contact

  • Gulhane Egitim ve Arastirma Hastanesi Tibbi Onkoloji Klinigi

    RECRUITING

    Ankara, Turkey (Türkiye)

    Contact

  • Guy's and St Thomas' NHS Foundation Trust

    RECRUITING

    London, United Kingdom

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hacettepe University Medical Faculty

    RECRUITING

    Ankara, Turkey (Türkiye)

    Contact

  • Helios Klinikum Wuppertal

    RECRUITING

    Wuppertal, Germany

    Contact

  • Henry Ford Hospital

    RECRUITING

    Detroit, Michigan, 48202, United States

    Contact

  • Hospital Clinic De Barcelona

    RECRUITING

    Barcelona, 08036, Spain

    Contact

  • Hospital Clínico San Carlos

    RECRUITING

    Madrid, Spain

    Contact

  • Hospital Universitari Vall D Hebron

    RECRUITING

    Barcelona, Spain

    Contact

  • Hospital Universitario Quirónsalud Madrid

    RECRUITING

    Madrid, Spain

    Contact

  • Hospital Universitario Virgen del Rocío

    RECRUITING

    Valencia, Spain

    Contact

  • Hôpital Morvan - CHRU de Brest - cancérologie et d'hématologie

    RECRUITING

    Brest, France

    Contact

  • Hôpital de la Pitiê Salpêtriêre

    RECRUITING

    Paris, 75103, France

    Contact

  • IEO - Istituto Europeo di Oncologia, IRCCS

    RECRUITING

    Milan, Italy

    Contact

  • IRCCS Policlinico San Matteo, Università degli studi di Pavia, Pavia Fondazione IRCCS Policlinico San Matteo

    RECRUITING

    Pavia, Italy

    Contact

  • Institut Claudius Regaud

    RECRUITING

    Toulouse, 31100, France

    Contact

  • Institut de Cancerologie de l'Ouest site Paul Papin

    RECRUITING

    Angers, France

    Contact

  • Interbalkan European Medical Center

    RECRUITING

    Thessaloniki, 57001, Greece

    Contact

  • Istituto Nazionale dei Tumori - Fondazione Pascale, IRCCS

    RECRUITING

    Napoli, Italy

    Contact

  • Istituto Oncologico Veneto IOV - IRCCS

    RECRUITING

    Padua, Italy

    Contact

  • Istituto Romagnolo per lo Studio dei Tumori Dino Amadori - IRST IRCCS

    RECRUITING

    Meldola, Italy

    Contact

  • Istituto di Candiolo, IRCCS

    RECRUITING

    Candiolo, Italy

    Contact

  • Klinikum Bayreuth GmbH

    RECRUITING

    Bayreuth, 95445, Germany

    Contact

  • Klinikum Worms gGmbH

    RECRUITING

    Worms, 67550, Germany

    Contact

  • Medipol Mega Hospital - Medical Oncology

    RECRUITING

    Istanbul, Turkey (Türkiye)

    Contact

  • Medizinische Hochschule Hannover

    RECRUITING

    Hanover, Germany

    Contact

  • Memorial Ankara Hastanesi Tibbi Onkoloji

    RECRUITING

    Ankara, Turkey (Türkiye)

    Contact

  • Metropolitan Hospital [Oncology]

    RECRUITING

    Piraeus, 12462, Greece

    Contact

  • Miami Valley Hospital South

    RECRUITING

    Centerville, Ohio, 45459, United States

    Contact

  • National and Capodistrian University of Athens - University General Hospital Attikon

    RECRUITING

    Athens, 12462, Greece

    Contact

  • Oregon Health & Science University

    COMPLETED

    Portland, Oregon, 97239, United States

  • Ospedale San Gerardo, ASST di Monza, IRCCS

    RECRUITING

    Monza, Italy

    Contact

  • Prof. Dr. Suleyman Yalcin Sehir Hastanesi

    RECRUITING

    Istanbul, Turkey (Türkiye)

    Contact

  • Providence Medical Foundation

    RECRUITING

    Fullerton, California, 92835, United States

    Contact

  • SCRI Oncology Partners

    RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact

  • Samsung Medical Center

    RECRUITING

    Seoul, 06351, South Korea

    Contact

  • Seoul National University Bundang Hospital

    RECRUITING

    Seoul, South Korea

    Contact

  • Seoul National University Hospital

    RECRUITING

    Seoul, South Korea

    Contact

  • The Christie NHS Foundation Trust - Medical Oncology

    RECRUITING

    Manchester, M20 4BX, United Kingdom

    Contact Phone: •••-•••-••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Clatterbridge Cancer Centre NHS Foundation Trust

    WITHDRAWN

    Liverpool, United Kingdom

  • UT Health San Antonio University of Texas

    COMPLETED

    San Antonio, Texas, 78229, United States

  • Uniklinik Koeln - Klinik und Poliklinik fuer Frauenheilkunde

    COMPLETED

    Cologne, Germany

  • Universitaetsklinikum Duesseldorf

    RECRUITING

    Düsseldorf, Germany

    Contact

  • Universitaire Ziekenhuizen Leuven - Campus Gasthuisberg

    RECRUITING

    Leuven, Belgium

    Contact

  • Universitatsklinikum Carl Gustav Carus

    RECRUITING

    Dresden, Germany

    Contact

  • Universite Catholique de Louvain (UCL) - Cliniques Universitaires Saint-Luc

    RECRUITING

    Woluwe-Saint-Lambert, Belgium

    Contact

  • University Clinical Hospital Virgen de la Arrixaca

    RECRUITING

    El Palmar, Murcia, 30120, Spain

    Contact

  • University College London Hospitals NHS Foundation Trust - University College Hospital (UCH) - Macmillan Cancer Centre

    RECRUITING

    London, United Kingdom

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital 12 de Octubre

    RECRUITING

    Madrid, Madrid, 28041, Spain

    Contact

  • University Hospital Ramón y Cajal

    RECRUITING

    Madrid, Madrid, 28034, Spain

    Contact

  • University Hospital Reina Sofía

    RECRUITING

    Córdoba, Andalusia, 14004, Spain

    Contact

  • University Hospitals of Leicester NHS Trust -Glenfield Hospital

    WITHDRAWN

    Leicester, United Kingdom

  • University of Texas MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

  • Universitätsklinikum Erlangen

    RECRUITING

    Erlangen, Germany

    Contact

  • Universitätsklinikum Leipzig

    RECRUITING

    Leipzig, Germany

    Contact

  • Virginia Cancer Institute

    RECRUITING

    Norfolk, Virginia, 00115, United States

    Contact

Conditions

Explore the condition pages connected to this study.

BRAIN DISEASES BRAIN NEOPLASMS BREAST DISEASES BREAST NEOPLASMS CENTRAL NERVOUS SYSTEM DISEASES CENTRAL NERVOUS SYSTEM NEOPLASMS NEOPLASMS NEOPLASMS BY SITE