Stemline Therapeutics, Inc.

This study is testing a new three-drug combination for adults with a specific type of acute myeloid leukemia (AML) who are too old or frail for standard intensive chemotherapy. The goal is to see if adding a drug called tagraxofusp to two existing drugs (venetoclax and azacitidin…

This study is testing a new drug, elacestrant, combined with other cancer medicines to see if they can better control advanced breast cancer that has spread. It will involve about 435 adults whose cancer has worsened despite prior hormone therapy. The first part finds safe doses,…

This is the first time researchers are testing a new drug called MEN2501 in people with ovarian cancer that has stopped responding to standard platinum-based chemotherapy. The study aims to find a safe dose, understand how the drug works in the body, and see if it can help contro…

This study is testing whether two drugs, elacestrant and abemaciclib, work together to control breast cancer that has spread to the brain. It will involve about 73 adults whose cancer is fueled by estrogen and has spread to the brain. The first part finds the safest dose, and the…

This is the first human study testing an experimental drug called MEN2312 for people with advanced breast cancer that has stopped responding to standard treatments. The trial aims to find the safest and most effective dose, testing the drug alone and in combination with other the…

This large, global study is testing whether a new drug called elacestrant works better than standard hormone therapy at keeping breast cancer from returning. It will involve over 4,200 people with a specific type of early-stage breast cancer that has spread to lymph nodes and has…