New hope for breast cancer: elacestrant trial targets tumors without prior CDK4/6 drugs

NCT ID NCT05596409

First seen Apr 25, 2026 · Last updated May 08, 2026 · Updated 3 times

Summary

This study tests a drug called elacestrant in 61 people with a common type of advanced breast cancer (ER+/HER2-). Participants have not received a specific class of drugs (CDK4/6 inhibitors) before. The goal is to see if elacestrant can slow or stop cancer growth over 6 months.

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Contacts and locations

Locations

  • COMPLEX ONCOLOGICAL CENTER - Shumen

    Shumen, 9700, Bulgaria

  • Centro De Pesquisa Clinica DO Hospital Sirio-Libanes - UNIDADE Brasilia

    Brasília, 70200-730, Brazil

  • Centro de Estudos e Pesquisas de Hematologia e Oncologia- CEPHO

    Santo André, São Paulo, 09060-650, Brazil

  • Centro de Pesquisas Clinicas em Oncologia (Center for Clinical Research in Oncology (CPCO)) - Hospital Evangélico de Cachoeiro de Itapemirim

    Cachoeiro de Itapemirim, Espírito Santo, 29308-014, Brazil

  • Centro de Pesquisas Oncologicas

    Florianópolis, Santa Catarina, 88034-000, Brazil

  • Clinica de Pesquisas e Centro de Estudos Em Oncologia Ginecologica e Mamaria Ltda

    São Paulo, 01317-001, Brazil

  • Complex Oncology Center

    Plovdiv, 4000, Bulgaria

  • Comprehensive Cancer Centers of Nevada

    Las Vegas, Nevada, 89128, United States

  • Fucam, Ac.

    Mexico City, 4980, Mexico

  • Highlands Oncology Group, PA

    Springdale, Arkansas, 72762, United States

  • Hospital São Lucas PUCRS - Centro de Pesquisa em Oncologia (CPO)

    Porto Alegre, Rio Granda Do Sul, 70200-730, Brazil

  • Hospital de Amor de Barretos

    Barretos, São Paulo, 14784-400, Brazil

  • Hospital de Clinicas de Porto Alegre

    Porto Alegre, Rio Granda Do Sul, 90035, Brazil

  • I CAN Oncology Center, Centro Medico AVE

    Monterrey, Nuevo León, 64710, Mexico

  • Innova Medical Center

    Tbilisi, 179, Georgia

  • Institute of Clinical Oncology

    Tbilisi, Georgia

  • Institutul Oncologic "Prof. Dr. Ion Chiricuta" Cluj Napoca

    Cluj-Napoca, Cluj, 400150, Romania

  • LTD Simon Khechinashvili University Clinic

    Tbilisi, 179, Georgia

  • Northwestern University, Northwestern Feinberg School of Medicine Prentice Women's Hospital

    Chicago, Illinois, 60611, United States

  • Torre Medica Hospital Dalinde

    Mexico City, 06760, Mexico

  • UT Health San Antonio Mays Cancer Center

    San Antonio, Texas, 78229, United States

  • Unidad Médica Onco-Hematológica

    Puebla City, 4515, Mexico

Conditions

Explore the condition pages connected to this study.