CENTRAL NERVOUS SYSTEM NEOPLASMS
Clinical trials for CENTRAL NERVOUS SYSTEM NEOPLASMS explained in plain language.
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New hope for breast cancer patients with brain tumors: drug combo enters human trials
Disease control Recruiting nowThis study tests two drugs, elacestrant and abemaciclib, in people whose breast cancer has spread to the brain. The goal is to see if the combination can shrink or control brain tumors. About 73 adults with ER-positive, HER2-negative breast cancer will take part. The study is cur…
Matched conditions: CENTRAL NERVOUS SYSTEM NEOPLASMS
Phase: PHASE1, PHASE2 • Sponsor: Stemline Therapeutics, Inc. • Aim: Disease control
Last updated May 16, 2026 23:38 UTC
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New pill takes on brain tumors: first human trial begins
Disease control Recruiting nowThis early-stage trial tests an oral drug called ONC206 in adults with brain tumors that have come back. The main goal is to find the safest dose and understand side effects. About 102 participants will receive the drug weekly or multiple days per week.
Matched conditions: CENTRAL NERVOUS SYSTEM NEOPLASMS
Phase: PHASE1 • Sponsor: Jazz Pharmaceuticals • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Engineered immune cells injected directly into brain to fight childhood tumors
Disease control Recruiting nowThis early-stage trial tests a new treatment for children and young adults (up to age 21) with certain brain tumors that have come back or not responded to standard therapy. The treatment uses the patient's own immune cells, which are modified in a lab to recognize and attack a p…
Matched conditions: CENTRAL NERVOUS SYSTEM NEOPLASMS
Phase: PHASE1 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated May 15, 2026 11:53 UTC