Can computer games clear the fog? new study tests brain training for ME/CFS

NCT ID NCT07523113

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two brain-training programs for adults with ME/CFS who experience brain fog. Both programs include computer games and a mild nerve stimulation device, but one focuses on processing speed and daily tasks while the other emphasizes relaxation and healthy habits. Thirty participants will train remotely over 2-4 weeks and be followed for 6 months to see if their thinking and daily activities improve.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

brain training (computer games and lifestyle coaching) plus non-invasive vagus nerve stimulation

What this could lead to

If it works, this could point toward a practical, at-home way to reduce brain fog and improve daily functioning for people with ME/CFS.

What could go wrong

This is a very small, early-stage study with only 30 participants. The two approaches are compared head-to-head, so neither may prove clearly better. Results may not apply to everyone with brain fog.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cognitive disorder Cognitive Dysfunction long COVID-19 Mental Fatigue myalgic encephalomeyelitis/chronic fatigue syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35294, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••