Scientists zap brains to unlock secrets of satiety

NCT ID NCT06105164

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study uses a noninvasive brain stimulation technique called TMS to investigate how the cerebellum influences feelings of fullness and eating behavior. Researchers will compare brain activity and food choices in 150 healthy adults after they eat or fast. The goal is to better understand the brain circuits involved in appetite control, which could inform future obesity treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Repetitive Transcranial Magnetic Stimulation (rTMS)

What this could lead to

If successful, this could reveal a brain circuit that controls appetite, pointing toward new treatments for obesity.

What could go wrong

This is an early-stage, observational study in healthy people, not a treatment trial. It may not translate into real-world weight-loss solutions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Appetitive Behavior Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02120, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • McLean Hospital

    RECRUITING

    Belmont, Massachusetts, 02478, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••