Brain scans reveal why some shed pounds after Weight-Loss surgery and others Don't
NCT ID NCT05359887
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study uses PET scans to look at the brain's reward system in 30 people who had bariatric surgery 2-3 years ago. Researchers want to see if differences in dopamine receptors explain why some patients lose more weight than others. Participants will have brain scans before and after a liquid meal to measure these changes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- standardized liquid mixed meal (Nutridrink)
- What this could lead to
- If successful, this could help explain why some people lose more weight after bariatric surgery, potentially leading to better support or treatments for those who struggle.
- What could go wrong
- This is a small, early observational study with only 30 participants. It does not test a new treatment, so it may not lead to direct changes in care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
MCL
Leeuwarden, Netherlands
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Other studies related to the condition(s) this trial covers.
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