Brain scans reveal why some shed pounds after Weight-Loss surgery and others Don't
NCT ID NCT05359887
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study uses PET scans to look at the brain's reward system in 30 people who had bariatric surgery 2-3 years ago. Researchers want to see if differences in dopamine receptors explain why some patients lose more weight than others. Participants will have brain scans before and after a liquid meal to measure these changes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
standardized liquid mixed meal (Nutridrink)
What this could lead to
If successful, this could help explain why some people lose more weight after bariatric surgery, potentially leading to better support or treatments for those who struggle.
What could go wrong
This is a small, early observational study with only 30 participants. It does not test a new treatment, so it may not lead to direct changes in care.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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MCL
Leeuwarden, Netherlands