Brain surgery breakthrough? scientists decode how electrical mapping affects the brain
NCT ID NCT06391294
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at how electrocortical stimulation (ECS) affects brain cells and speech areas during brain surgery for epilepsy or tumors. Researchers will have 65 participants perform simple tasks while their brains are mapped, sometimes with mild cooling. The goal is to understand how ECS works, which could lead to shorter surgeries and better outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
focal cortical cooling
What this could lead to
If successful, this study could help surgeons perform faster, more precise brain surgeries by better understanding how brain mapping works.
What could go wrong
This is an early-stage observational study with only 65 participants, so findings may not apply to all patients. The cooling procedure is painless but may not reveal clear insights.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Johns Hopkins University
Baltimore, Maryland, 21218, United States
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Northwestern University
Chicago, Illinois, 60611, United States
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University of Iowa
Iowa City, Iowa, 52242, United States