New brain implant aims to stop seizures before they start

NCT ID NCT05439655

Ongoing Knowledge-focused Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 21, 2026 · Updated 3 times

Summary

This study tests a new brain implant system (CorTec Brain Interchange) in 12 people with drug-resistant epilepsy. The device records brain signals at high speed to detect abnormal activity that may lead to seizures. Unlike current devices that wait for a seizure to start, this system aims to deliver stimulation early to prevent seizures. For now, the device is used externally in the hospital to see if it can reliably capture these signals.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: CorTec Brain Interchange (BIC) system
What this could lead to: If successful, this could lead to a future implant that stops seizures before they start by detecting early brain signals.
What could go wrong: This is a very early feasibility study with only 12 people. The device is not yet implanted, and the main goal is just to test data recording, not health outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EPILEPSY

Contacts and locations

Locations

Baylor College of Medicine

Houston, Texas, 77030-3498, United States
Mayo Clinic

Rochester, Minnesota, 55905, United States

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