ICU Survivors' brain health under the microscope

NCT ID NCT00392795

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 826 ICU survivors to understand why some develop long-term thinking and memory problems. Researchers will look at factors like delirium and sedative use during the ICU stay. The goal is to find modifiable risks that could lead to better prevention and recovery strategies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could identify which factors in the ICU cause long-term brain problems, pointing toward ways to prevent or treat them.

What could go wrong

This is an observational study, not a treatment trial. It may only find associations, not causes, and results might not apply to all ICU patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Cognition Disorders cognitive disorder Critical Illness delirium dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Saint Thomas Hospital

    Nashville, Tennessee, 37205, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States