Ultrasound implant blasts open brain barrier to deliver chemo in deadly cancer trial

NCT ID NCT04528680

First seen Apr 25, 2026 · Last updated May 23, 2026 · Updated 2 times

Summary

This trial tests an implantable ultrasound device that temporarily opens the blood-brain barrier, allowing chemotherapy to reach brain tumors more effectively. It involves 57 patients with recurrent glioblastoma, a fast-growing brain cancer. The goal is to find a safe dose and see if this approach can shrink tumors and extend survival.

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Contacts and locations

Locations

  • Northwestern Memorial Hospital

    Chicago, Illinois, 60611, United States

Conditions

Explore the condition pages connected to this study.