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New VA study aims to boost exercise adherence for knee arthritis sufferers

NCT ID NCT07219732

Symptom relief Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jul 24, 2026 · Updated 3 times

Summary

This study tests a program called BOOST-OA designed to help veterans with knee osteoarthritis stick to their home exercise routines. The program includes goal-setting tools during physical therapy and follow-up health coaching calls for 9 months after therapy ends. Researchers will measure whether participants have better physical function and less pain compared to those receiving standard physical therapy alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
behavioral intervention (BOOST-OA program)
What this could lead to
If it works, this could provide a simple, low-cost way to help people with knee osteoarthritis stay active and improve their daily function.
What could go wrong
This is a behavioral study, not a drug or device, so benefits may be modest. Results depend on participants' motivation and may not apply to non-veterans.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 360 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Dec 2030

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a US federal agency other than the NIH.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Diagnosis of knee OA (verified from the EHR) 2. Knee pain for 3 months 3. Knee pain on most days of the previous month, 4. Average knee pain 3 (on a scale of 0-10), 5. Self-report of some difficulty with walking or stair climbing. Exclusion Criteria: 1. Systemic rheumatic conditions, fibromyalgia, gout (knee) 2. Dementia, psychosis or active substance abuse disorder 3. Meniscus or knee ligament tear in the past 6 months 4. Lower extremity surgery in past 6 months or planned in next 9 months 5. Severe hearing or visual impairment 6. Serious / terminal illness 7. Hospitalization for a cardiovascular event, past 3 months 8. Unstable angina 9. History of ventricular tachycardia 10. Unstable chronic obstructive pulmonary disease 11. Uncontrolled hypertension (diastolic \>110 mm/Hg or systolic \> 200mm/Hg) 12. Stroke with moderate to severe aphasia 13. History of three or more falls in past 6 months 14. Resident of a long-term care facility 15. Other health problem that would prohibit safe participation in the study or home exercise 16. Current participation in another OA intervention study 17. Currently meeting Department of Health and Human Services physical activity recommendations 18. Completed PT for knee OA in the past year 19. Unable to speak sufficient English to participate in study activities

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Conditions

The condition(s) this trial relates to.

Health Behavior Motor Activity osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Osteoarthritis, knee

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Durham VA Medical Center, Durham, NC

    Durham, North Carolina, 27705-3875, United States

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