Blood test may predict knee osteoarthritis severity

NCT ID NCT07706569

First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time

Summary

This study examines whether two substances in the blood, Fetuin-A and COMP, are linked to the severity of knee osteoarthritis. Researchers will compare 120 people with knee osteoarthritis to 60 healthy volunteers, measuring their pain, mobility, and joint damage on X-rays. The goal is to see if these biomarkers could help doctors diagnose and monitor the disease more effectively.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could point toward a simple blood test to help diagnose knee osteoarthritis earlier and track its progression more accurately.
What could go wrong
This is an observational study, not a treatment trial. It may find no clear link between the biomarkers and disease severity, or the results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • S.B.U. Antalya Training and Research Hospital, Department of Physical Medicine and Rehabilitation

    RECRUITING

    Antalya, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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