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Which knee implant moves best? trial puts three designs to the test

NCT ID NCT03895489

Completed Disease control Sponsor: University of Alberta Source: ClinicalTrials.gov ↗

First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time

Summary

This trial compares three different knee replacement implants—Journey II, Stryker Triathlon, and Zimmer Persona—in people aged 50 to 75 with knee osteoarthritis. Researchers measure how well each implant restores knee movement, walking patterns, and function after surgery. The goal is to find out if one implant leads to better outcomes than the others.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
knee replacement implants (Journey II, Stryker Triathlon, Zimmer Persona)
What this could lead to
If one implant proves superior, it could guide surgeons toward a better option for knee replacement, improving mobility and reducing pain for patients.
What could go wrong
This is a small, early-stage trial with only 48 participants, so results may not apply to everyone. Differences between implants might be small or not clinically meaningful.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOARTHRITIS, KNEE

Contacts and locations

Locations

  • Edmonton Bone and Joint Centre

    Edmonton, Alberta, T5E 5R8, Canada

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