New pill aims to save your muscles while you shed pounds

NCT ID NCT07411378

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests if an experimental drug called BIO101 can help prevent muscle weakness in people taking the weight-loss drug semaglutide. About 164 obese or overweight adults will take either BIO101 or a placebo pill twice daily for 21 weeks, along with semaglutide and a reduced-calorie diet. Researchers will measure changes in leg strength and overall physical function to see if BIO101 offers added benefit.

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Conditions

The condition(s) this trial relates to.

muscular atrophy Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.