New combo therapy targets tough colorectal cancer
NCT ID NCT05200442
First seen Nov 05, 2025 · Last updated Jun 09, 2026 · Updated 31 times
Summary
This study tests the safety and effectiveness of combining the experimental drug AVUTOMETINIB (VS-6766) with cetuximab in people with advanced colorectal cancer that has a KRAS mutation. It is for those whose cancer worsened after prior treatments or who cannot tolerate them. The goal is to find the best dose and see how well the combination shrinks tumors.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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University of Chicago Medical Center
Chicago, Illinois, 60615, United States
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.