New drug combo targets tough colorectal cancer

NCT ID NCT05200442

First seen Nov 05, 2025 · Last updated May 07, 2026 · Updated 23 times

Summary

This study is for people with advanced colorectal cancer that has a specific gene change called KRAS. The cancer has gotten worse after standard treatments. Researchers are testing if combining two drugs, AVUTOMETINIB and cetuximab, is safe and can shrink tumors. About 53 adults will take part for up to 24 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Chicago Medical Center

    RECRUITING

    Chicago, Illinois, 60615, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.