New cocktail of cancer drugs tested in advanced tumors
NCT ID NCT03217747
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests the safety and effectiveness of combining the immunotherapy drug avelumab with other treatments (utomilumab, ivuxolimab, or radiation) in 173 people with advanced cancers that have not responded to standard therapies. The goal is to find tolerable doses and see if these combinations can shrink tumors or slow disease progression.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- avelumab (immunotherapy drug) combined with utomilumab, ivuxolimab, or radiation therapy
- What this could lead to
- If successful, this could point toward new combination treatments that help control advanced cancers by boosting the immune system.
- What could go wrong
- This is an early-phase trial (Phase 1/2) with a small number of participants. The combinations may cause serious side effects or may not shrink tumors effectively.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
M D Anderson Cancer Center
Houston, Texas, 77030, United States
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