21,000 patients to test if aspirin can replace painful injections after hip fracture

NCT ID NCT06937372

Not yet recruiting Disease control Sponsor: Queen Mary University of London Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study will compare aspirin tablets to daily injections of low molecular weight heparin (LMWH) for preventing dangerous blood clots in people who break their hip. Over 21,000 patients aged 60 and older across 96 UK hospitals will take part. Hospitals will switch between the two treatments over time, and researchers will track outcomes using NHS databases. The goal is to see if aspirin is a safe, effective, and cheaper alternative to injections.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: aspirin
What this could lead to: If aspirin works as well as injections, it could make blood clot prevention after hip fracture simpler, cheaper, and more comfortable for patients.
What could go wrong: This is a pragmatic trial using routine data, not a blinded placebo study. Results may show aspirin is less effective or riskier than injections, and findings may not apply outside the UK.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hip fracture thrombotic disease venous thromboembolism prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIP FRACTURES VENOUS THROMBOEMBOLISM (VTE)

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