Can a common diabetes drug make arteries younger? VA launches new trial
NCT ID NCT06745063
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether empagliflozin, a drug used for diabetes, can make arteries less stiff in veterans with obesity. Fifty participants will take either the drug or a placebo daily for 12 weeks. Researchers will measure changes in arterial stiffness using a standard test. The goal is to see if this drug can improve blood vessel health beyond its usual use.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Empagliflozin (a diabetes drug being tested for artery health)
What this could lead to
If it works, this could point toward a new way to improve blood vessel health in people with obesity, potentially reducing heart risks.
What could go wrong
This is a small, early-phase trial with only 50 participants. The drug may not improve artery stiffness, and results may not apply to people without obesity or with other health conditions.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Harry S. Truman Memorial, Columbia, MO
RECRUITINGColumbia, Missouri, 65201-5275, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact