New knee shot aims to ease arthritis pain without surgery

NCT ID NCT06233474

Ongoing Symptom relief Sponsor: Enlivex Therapeutics Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new medicine called Allocetra for people with knee osteoarthritis. It is injected directly into the knee joint to see if it safely reduces pain and improves function. About 160 adults aged 45-80 with moderate knee arthritis will receive either Allocetra or a placebo. The goal is to measure pain relief and any side effects over 6 months.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOARTHRITIS, KNEE

Contacts and locations

Locations

Barzilai Medical Center

Ashkelon, 7830604, Israel
Hasharon Medical Center

Petah Tikva, 4937211, Israel
IMSP Institutul de Cardiologie

Chisinau, 2025, Moldova
IMSP Sptalul Clinic Municipal "Sfanta Treime"

Chisinau, 2068, Moldova
Ichilov - Tel Aviv Sourasky Medical Center

Tel Aviv, 6423906, Israel
Kaplan Medical Center

Rehovot, 7661041, Israel
Rambam Medical Center

Haifa, 7651211, Israel
Sanos Clinic Herlev

Herlev, 2730, Denmark
Sanos Clinic Nordjylland

Gandrup, 9362, Denmark
Sanos Clinic Syddanmark

Vejle, 7100, Denmark
Sheba Medical Center

Ramat Gan, 5266202, Israel
Spitalul Clininc Republican "T. Mosneaga"

Chisinau, 2025, Moldova

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