New drug aims to fortify fragile bones in brittle bone disease trial
NCT ID NCT07062588
First seen Jan 24, 2026 · Last updated May 16, 2026 · Updated 17 times
Summary
This study tests a new medicine called AGA2115 in adults with osteogenesis imperfecta (brittle bone disease) types I, III, or IV. The goal is to see if it safely increases bone density compared to a placebo. About 80 adults aged 18 to 75 will participate, and the main measure is change in spine bone density after 12 months.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Aarhus Universitetshospital - Medicinsk Endokrinologisk Afdeling (MEA) Ambulatoriet - Tage-Hansens Gade
NOT_YET_RECRUITINGAarhus, Denmark
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Adults Westmead Hospital
NOT_YET_RECRUITINGWestmead, Australia
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Assistance Publique-Hopitaux de Paris (AP-HP) - Hopital Lariboisiere
NOT_YET_RECRUITINGParis, France
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Cambridge University Hospitals NHS Foundation Trust-Addenbrooke's Hospital
NOT_YET_RECRUITINGCambridge, United Kingdom
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Erasmus MC
NOT_YET_RECRUITINGRotterdam, Netherlands
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Hopital Edouard Herriot
NOT_YET_RECRUITINGLyon, France
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Indiana University School of Medicine, Department of Medicine and Pediatrics Division of Endocrinology
RECRUITINGIndianapolis, Indiana, 46202, United States
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Instituto de Investigaciones Metabolicas Dr. Zanchetta - Sede Centro
NOT_YET_RECRUITINGBuenos Aires, Argentina
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Isala ziekenhuizen
NOT_YET_RECRUITINGZwolle, Netherlands
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Leiden University Medical Center (LUMC) - Centrum voor botkwaliteit
NOT_YET_RECRUITINGLeiden, Netherlands
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Lothian Health Board, Western General Hospital
NOT_YET_RECRUITINGEdinburgh, United Kingdom
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Monash University-Monash Medical Centre (MMC)
NOT_YET_RECRUITINGMelbourne, Australia
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Nemours/Alfred I. duPont Hospital for Children
NOT_YET_RECRUITINGWilmington, Delaware, 19803, United States
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New Mexico Clinical Research & Osteoporosis Center, Inc. (NMCROC)
RECRUITINGAlbuquerque, New Mexico, 87160, United States
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Odense Universitetshospital
NOT_YET_RECRUITINGOdense, Denmark
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Oregon Health & Science University (OHSU) - The Harold Schnitzer Diabetes Health Center (HSDHC) - Endocrinology Clinic
NOT_YET_RECRUITINGPortland, Oregon, 97239, United States
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Oxford University Hospitals NHS Foundation Trust
NOT_YET_RECRUITINGOxford, United Kingdom
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Phoenix Children's
NOT_YET_RECRUITINGPhoenix, Arizona, 85016, United States
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Royal Melbourne Hospital
NOT_YET_RECRUITINGParkville, Australia
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Royal National Orthopaedic Hospital NHS Trust
NOT_YET_RECRUITINGLondon, United Kingdom
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Royal North Shore Hospital (RNSH)
NOT_YET_RECRUITINGSaint Leonards, Australia
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The Ohio State University Wexner Medical Center (OSUWMC)
NOT_YET_RECRUITINGColumbus, Ohio, 43210, United States
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University Health Network - Toronto General Hospital - Osteoporosis Clinic
RECRUITINGToronto, Ontario, M5G 2C4, Canada
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University of Nebraska Medical Center (UNMC) - Diabetes and Endocrinology Center
NOT_YET_RECRUITINGOmaha, Nebraska, 68131, United States
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Vanderbilt University Medical Center (VUMC) - Eskind Diabetes Clinic
NOT_YET_RECRUITINGNashville, Tennessee, 37232, United States
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Washington University School of Medicine in St. Louis
NOT_YET_RECRUITINGSt Louis, Missouri, 63110, United States
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Yale University School of Medicine
NOT_YET_RECRUITINGNew Haven, Connecticut, 06510, United States
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Conditions
Explore the condition pages connected to this study.