Gentle exercise with cuffs may strengthen bones and muscles in brittle bone disease

NCT ID NCT07478224

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a safe, low-intensity exercise program using inflatable cuffs on the legs to improve muscle, bone, and quality of life in 40 adults with osteogenesis imperfecta type I (a mild form of brittle bone disease). Participants will do simple home exercises 2-3 times a week for 12 weeks. The goal is to see if this approach can build strength without risking fractures.

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Conditions

The condition(s) this trial relates to.

Motor Activity osteogenesis imperfecta osteogenesis imperfecta type 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Ghent University (Hospital) - department of endocrinology and department of rehabilitation sciences and physiotherapy

    RECRUITING

    Ghent, 9000, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••