Brittle bone breakthrough? drug may restore hearing

NCT ID NCT04152551

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether bisphosphonates, drugs commonly used to strengthen bones, can also treat hearing loss in people with Osteogenesis Imperfecta (OI) type I. Researchers will enroll 100 adults and children with OI, giving some the drug and comparing their hearing over time. The goal is to see if this treatment can slow or improve hearing loss that often starts early in life for people with OI.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OSTEOGENESIS IMPERFECTA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospital for Special Surgery

    RECRUITING

    New York, New York, 10021, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

More trials for these conditions

Other studies related to the condition(s) this trial covers.