New hope for brittle bones: experimental drug enters phase 2 trial in china

NCT ID NCT07557446

First seen May 06, 2026 · Last updated May 15, 2026 · Updated 2 times

Summary

This study tests an experimental drug called AGA2115 in 48 Chinese adults and adolescents with types I, III, or IV osteogenesis imperfecta (brittle bone disease). The goal is to find the best dose and check for side effects, while also measuring changes in bone density over 12 months. Participants must have a confirmed genetic diagnosis and low bone density to join.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Hospital of Soochow University

    Suzhou, Jiangsu, 215025, China

    Contact

  • Chinese Academy of Medical Sciences, Peking Union Medical College Hospital

    Beijing, Beijing Municipality, 100005, China

    Contact

  • Shanghai Sixth People's Hospital

    Shanghai, Shanghai Municipality, 200233, China

    Contact

  • The University of Hong Kong-Shenzhen Hospital

    Shenzhen, Guangdong, 518053, China

    Contact

Conditions

Explore the condition pages connected to this study.