Osteogenesis imperfecta type 3
MONDO:0009804Osteogenesis imperfecta type III is a severe type of osteogenesis imperfecta (OI), a genetic disorder characterized by increased bone fragility, low bone mass and susceptibility to bone fractures. The main signs of type III include very short stature, a triangular face, severe scoliosis, grayish sclera, and dentinogenesis imperfecta (DI).
Also known as: OI type 3, OI3, osteogenesis imperfecta type 3, osteogenesis imperfecta type III, progressive deforming osteogenesis imperfecta, severe osteogenesis imperfecta, OI type III, OI, type 3
9 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
-
New shot aims to fortify fragile bones in brittle bone disease trial
Disease control Recruiting nowThis study tests a drug called AGA2115 in 80 adults with osteogenesis imperfecta (brittle bone disease) types I, III, or IV. Participants receive either the drug or a placebo as a shot under the skin. The main goal is to see if the drug increases bone density in the spine after 1…
Phase: PHASE2 • Sponsor: Angitia Incorporated Limited • Aim: Disease control
Last updated Aug 18, 2026 02:00 UTC
-
New shot aims to toughen fragile bones in rare disease
Disease control Recruiting nowThis phase 2 trial tests a drug called AGA2115 in 48 Chinese adults and adolescents with osteogenesis imperfecta (types I, III, IV), a condition that makes bones brittle. Participants receive one of three dose schedules by injection under the skin. The study checks for side effec…
Phase: PHASE2 • Sponsor: Angitia Biopharmaceuticals Guangzhou Limited • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC