Brittle bones, fragile hearts? new study investigates cardiac risks in OI

NCT ID NCT07287241

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is observing 40 people with osteogenesis imperfecta (brittle bone disease) to see how often heart problems occur. Researchers will use standard heart tests like echocardiograms to check for issues. The goal is to create better screening guidelines to catch heart problems early and improve care for people with OI.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could lead to better heart screening guidelines for people with osteogenesis imperfecta, potentially improving their long-term health and quality of life.

What could go wrong

This is a small observational study, so it cannot prove cause and effect. Results may not apply to all people with OI, and it won't test any new treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bone disorder hereditary disease musculoskeletal system disorder osteogenesis imperfecta

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • IRCCS Istituto Ortopedico Rizzoli

    RECRUITING

    Bologna, Emilia-Romagna, 40136, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact