Which exercise eases knee pain best? new trial aims to find out

NCT ID NCT07302204

Recruiting now Symptom relief Sponsor: University of Nove de Julho Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two exercise programs for people with knee osteoarthritis: supervised cycling on a stationary bike and a land-based therapeutic exercise program with strengthening and balance training. The goal is to see which approach better reduces pain sensitivity during and after exercise. Ninety adults aged 45 to 75 with knee osteoarthritis will participate over ten weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: exercise (aerobic cycling or therapeutic exercises)
What this could lead to: If successful, this study could show that a specific type of exercise is better at reducing pain sensitivity in people with knee osteoarthritis, helping guide more effective non-drug treatments.
What could go wrong: This is a relatively small, early-stage trial (90 participants) comparing two exercise types. The results may not apply to all patients, and the primary outcome is a lab measure of pain threshold, not necessarily long-term pain relief.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOARTHRITIS OF THE KNEE

Contacts and locations

Locations

Cid André Fidelis de Paula Gomes
NOT_YET_RECRUITING

São Paulo, 01415000, Brazil
Nove de Julho University
RECRUITING

São Paulo, 01504-001, Brazil

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