Which exercise eases knee pain best? new trial aims to find out

NCT ID NCT07302204

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two exercise programs for people with knee osteoarthritis: supervised cycling on a stationary bike and a land-based therapeutic exercise program with strengthening and balance training. The goal is to see which approach better reduces pain sensitivity during and after exercise. Ninety adults aged 45 to 75 with knee osteoarthritis will participate over ten weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

exercise (aerobic cycling or therapeutic exercises)

What this could lead to

If successful, this study could show that a specific type of exercise is better at reducing pain sensitivity in people with knee osteoarthritis, helping guide more effective non-drug treatments.

What could go wrong

This is a relatively small, early-stage trial (90 participants) comparing two exercise types. The results may not apply to all patients, and the primary outcome is a lab measure of pain threshold, not necessarily long-term pain relief.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cid André Fidelis de Paula Gomes

    NOT_YET_RECRUITING

    São Paulo, 01415000, Brazil

    Contact Email: •••••@•••••

  • Nove de Julho University

    RECRUITING

    São Paulo, 01504-001, Brazil

    Contact

    Contact