Aerobic exercise may boost mobility in leg lymphedema patients
NCT ID NCT07414615
First seen Jun 25, 2026 · Last updated Jul 14, 2026 · Updated 3 times
Summary
This study tests whether adding aerobic exercise to standard lymphedema therapy (complex decongestive physiotherapy) can improve walking, balance, leg strength, and daily function. Twenty-four adults with bilateral lower limb lymphedema will be randomly assigned to either standard therapy alone or standard therapy plus aerobic training. The goal is to see if the extra exercise leads to better movement and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- aerobic exercise training
- What this could lead to
- If it works, this could show that adding aerobic exercise to standard lymphedema therapy improves walking, balance, and leg function.
- What could go wrong
- This is a small, early-stage study with only 24 participants, so results may not apply to everyone. The exercise program is supervised and low-risk, but benefits may be modest.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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24 people
The number who actually took part.
- Started
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Feb 2026
- Finished
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May 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged between 20 and 60 years * Diagnosed with bilateral lower extremity lymphedema * Completion of chemotherapy, radiotherapy, or other oncological treatments, with no oncological contraindication to participation * Signed written informed consent * Willingness to participate in the study Exclusion Criteria: * Presence of uncontrolled cardiac or pulmonary disease * Presence of renal insufficiency * Presence of musculoskeletal or neurological disorders affecting mobility or balance * Presence of systemic or local infection in the lower extremity * Impaired independent ambulation or use of assistive walking devices * Pregnancy * Presence of visual, cognitive, or intellectual impairment that may interfere with participation in assessment or intervention procedures
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Bezmialem Vakif University
Istanbul, Turkey (Türkiye)
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