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Could online therapy ease the swelling of breast cancer lymphedema?

NCT ID NCT07794904

Symptom relief Sponsor: Istanbul University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 31, 2026 · Last updated Sep 09, 2026 · Updated 4 times

Summary

This trial tests whether a live online exercise and self-drainage program can reduce arm swelling in women with breast cancer-related lymphedema. Researchers will compare women who join live video sessions with a therapist to those who follow the same program at home using a brochure. The study includes 64 women aged 20 to 65 with stage I or II lymphedema. The main goal is to see if the supervised online approach leads to greater improvements in arm volume and swelling.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Tele-rehabilitation-based exercise and self-lymphatic drainage program delivered via live online sessions
What this could lead to
If it works, this could offer a convenient, home-based way to reduce arm swelling and improve daily life for women with breast cancer-related lymphedema.
What could go wrong
The trial is small and early, and results may not apply to all patients. Live online sessions may not match in-person care, and some women might find the program hard to follow.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 64 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2026

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 65 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * Female participants between 20 and 65 years of age * History of unilateral breast cancer surgery including axillary lymph node dissection * Completion of breast cancer treatments, including surgery, radiotherapy, and chemotherapy, with at least 3 months elapsed since treatment completion * Diagnosis of stage I or stage II upper extremity lymphedema according to the International Society of Lymphology (ISL) classification * Presence of at least 5% volume difference between the affected and unaffected upper extremities * No history of manual lymphatic drainage, compression bandaging treatment, or structured resistance exercise program within the previous 3 months * Ability to use a smartphone or tablet and sufficient cognitive and motor ability to participate in digital sessions * Prescription of an appropriate compression garment for the affected extremity and regular use of the garment as recommended Exclusion Criteria * Presence of uncontrolled hypertension, pulmonary edema, or severe cardiovascular disease * Presence of psychiatric or cognitive impairment that may interfere with study participation or adherence * Presence of stage III lymphedema according to the ISL classification * Presence of skin lesions such as papilloma or hyperkeratosis in the lymphedematous area * History of bilateral breast cancer * Presence of active cancer or clinical/radiological evidence of metastasis * Presence of active infection in the affected extremity

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Conditions

The condition(s) this trial relates to.

Breast Cancer Lymphedema lymphedema Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer-related lymphedema Lymphedema

Contacts and locations

Locations

  • Istanbul Unıversity, Istanbul Faculty of Medicine, Department of Physical Medicine and Rehabilitation

    Istanbul, Fatih, 34093, Turkey (Türkiye)

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