Can a Thigh-Worn sensor outsmart dizziness questionnaires?

NCT ID NCT04782830

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This study explores whether a small accelerometer worn on the thigh can objectively measure how well treatments work for neurogenic orthostatic hypotension—a condition causing dizziness and fainting upon standing. Participants wear the device for one week on placebo and one week on their usual medication (midodrine or atomoxetine). The goal is to see if upright time measured by the device matches or outperforms symptom questionnaires in assessing treatment effectiveness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

accelerometer (Activpal device)

What this could lead to

If successful, this could provide a more objective way to measure how well treatments for orthostatic hypotension work, improving future care.

What could go wrong

This is a small, early-stage study focused on measurement methods, not a treatment itself. The device may not prove superior to standard questionnaires.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Hypotension, Orthostatic hypotensive disorder multiple system atrophy Parkinson disease parkinsonian disorder primary orthostatic hypotension pure autonomic failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Autonomic Dysfunction Center/ Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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