3D-Guided heat therapy targets enlarged prostate without cutting

NCT ID NCT05443451

Completed Symptom relief Sponsor: Chinese University of Hong Kong Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tests a new way to treat urinary symptoms caused by an enlarged prostate. Using 3D ultrasound guidance, doctors insert a thin needle through the skin between the scrotum and anus to deliver microwave heat directly to the overgrown prostate tissue. The approach aims to shrink the prostate while protecting the bladder neck and urethra. The study enrolls 12 men over age 50 with moderate-to-severe symptoms and a prostate size between 30 and 80 cc.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: microwave ablation device
What this could lead to: If successful, this could offer a less invasive treatment option for men with enlarged prostate, reducing urinary symptoms while preserving sexual function.
What could go wrong: This is a very small pilot study with only 12 participants, so results may not apply to all men. The procedure carries risks such as bleeding, infection, or damage to nearby structures.

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Conditions

The condition(s) this trial relates to.

benign prostatic hyperplasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE HYPERPLASIA

Contacts and locations

Locations

Prince of Wales Hospital

Hong Kong, Hong Kong

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