Weill Medical College Of Cornell University

This study compares two common procedures to restore blood flow in the heart for 600 minority patients with coronary artery disease. One method uses a small mesh tube (stent) inserted through the wrist or groin, while the other is open-heart bypass surgery using blood vessels fro…

This study tests whether eating only during an 8-hour window each day, combined with a healthy diet and exercise, can reduce liver fat in people with non-alcoholic fatty liver disease. About 40 adults with high liver fat will be assigned to either time-restricted eating plus stan…

This study looks at 2,300 women having heart bypass surgery to see if using multiple arteries (instead of just one) leads to fewer heart problems and better quality of life. Participants are randomly assigned to one of the two surgical approaches. The goal is to find the best way…

This study is testing a new way to personalize a non-drug depression treatment called rTMS, which uses magnetic pulses to stimulate the brain. Researchers will use a special brain scan (fMRI) to categorize a person's depression and then assign them to receive rTMS targeted to a s…

This early-stage study tests a new vaccine called dAd5GNE in 150 people who are dependent on cocaine. The vaccine aims to train the body's immune system to block cocaine from reaching the brain, reducing its effects. The main goal is to check if the vaccine is safe, while also lo…

This study tests whether a mobile app called MAYA, which provides cognitive behavioral therapy, is practical and helpful for adults aged 40-79 who have had a stroke and are experiencing anxiety or depression. Ten participants will use the app and provide feedback on its quality a…

This study tests if a safe, gentle electrical current applied to the forehead at home can reduce severe tiredness after a stroke. Researchers will enroll 24 adults who are at least 3 months past their first stroke and have significant fatigue. Participants will use a headset devi…

This study tests whether a specially designed video game can reduce how often teens have sex without using birth control. About 850 teens aged 15-20 will either play the game or do a different activity. Researchers will track changes in their contraceptive use over 9 months.

This study is testing a special shoe called NUSHU that has sensors to measure how people with Parkinson's disease walk and keep their balance. The shoe can also give gentle vibrations to help with walking problems. About 40 people with early to advanced Parkinson's and healthy vo…

This study uses cardiac MRI to examine the hearts and lungs of 510 COVID-19 survivors who had moderate to severe illness. The goal is to find out why some people continue to have symptoms like shortness of breath and fatigue months after recovery. Participants will undergo imagin…

This study follows over 22,000 children and adults with genetic developmental and epileptic encephalopathy (DEE) to learn how the disease changes over time. Participants join in-person visits, virtual visits, or online surveys. No treatments are tested; the goal is to gather data…

This study compares an online genetic testing service with standard care for first-degree relatives of people with BRCA1 or BRCA2 mutations. The goal is to see if the online approach helps more relatives complete genetic testing within 6 months. About 820 participants will be enr…

This early-phase study tests whether the drug propranolol can stimulate heart muscle cells to divide and grow in infants born with Tetralogy of Fallot, a serious heart defect. About 40 babies under 60 days old will receive propranolol before routine heart surgery. Researchers wil…

This study collects blood, airway, and urine samples from 2,000 healthy volunteers and people with lung diseases like COPD and pulmonary fibrosis. The goal is to establish normal ranges and compare genetic patterns in airway cells to better understand how lung diseases develop. N…