Heart healing hope: Beta-Blocker may spark new muscle growth in infants
NCT ID NCT04713657
First seen Nov 18, 2025 · Last updated Apr 24, 2026 · Updated 17 times
Summary
This early-phase study tests whether the drug propranolol can stimulate heart muscle cells to divide and grow in infants born with Tetralogy of Fallot, a serious heart defect. About 40 babies under 60 days old will receive propranolol before routine heart surgery. Researchers will examine discarded heart tissue to see if new muscle cells formed. The goal is to understand how heart regeneration works, not yet to cure or treat heart failure.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Children's Hospital of Philadelphia
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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Upmc Children'S Hospital of Pittsburgh
RECRUITINGPittsburgh, Pennsylvania, 15224, United States
Contact
Contact Email: •••••@•••••
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Weill Cornell Medicine
RECRUITINGNew York, New York, 10065, United States
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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