Mailed DNA kits could boost cancer prevention in families

NCT ID NCT04613440

Ongoing Knowledge-focused Sponsor: Weill Medical College of Cornell University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 01, 2026 · Updated 3 times

Summary

This study tests whether offering online educational videos and mailed saliva genetic testing kits helps more first-degree relatives of people with BRCA mutations get tested, compared to standard care with a family letter. About 820 participants will be enrolled across several medical centers. The goal is to see if this approach increases testing rates and encourages risk-reducing behaviors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Educational video and mailed saliva kit for genetic testing
What this could lead to: If successful, this could make it easier for family members of BRCA carriers to get tested, helping them take steps to prevent cancer.
What could go wrong: This is an early-stage study comparing two approaches, so it may not show a clear benefit. Results depend on relatives choosing to participate.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRCA1 MUTATION BRCA2 MUTATION

Contacts and locations

Locations

Duke University

Durham, North Carolina, 27710, United States
MD Anderson Cancer Center

Houston, Texas, 77030, United States
Weill Cornell Medicine

New York, New York, 10065, United States

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