Wake Forest University Health Sciences
Clinical trials sponsored by Wake Forest University Health Sciences, explained in plain language.
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Hernia mesh Face-Off: which patch holds better?
Disease control TerminatedThis study aimed to compare two brands of surgical mesh used to repair a common type of abdominal hernia. It looked at how often the hernia came back and if there were complications with each mesh. The trial was very small and was stopped early, so no clear results are available.
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New combo attack on spine cancer
Disease control TerminatedThis early-stage study tested whether combining a precise form of radiation (radiosurgery) with an immunotherapy drug (pembrolizumab) is safe and feasible for people with aggressive spinal tumors. The main goal was to see if patients could complete both treatments. Researchers al…
Phase: EARLY_PHASE1 • Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New combo attack on aggressive sarcomas
Disease control TerminatedThis early-stage study tested the safety of combining two chemotherapy drugs (gemcitabine and docetaxel) with radiation before surgery for adults with large, high-grade soft tissue sarcomas in their arms or legs. The main goal was to find the highest dose patients could tolerate …
Phase: PHASE1 • Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Mouth-Delivered electromagnetic waves tested in battle against liver cancer
Disease control TerminatedThis study tested if adding a novel electromagnetic field treatment, delivered through the mouth, could improve outcomes for people with advanced liver cancer when used with the drug regorafenib. It aimed to see if this combination could help control the cancer longer than regora…
Phase: PHASE2 • Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated Mar 06, 2026 15:38 UTC
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Spinal implant tested to zap diabetic pain
Symptom relief TerminatedThis study aimed to see if a spinal cord stimulator could help reduce pain in people with painful diabetic neuropathy. It involved implanting a small device that sends electrical pulses to the spinal cord. The goal was to see if this treatment, along with standard medications, co…
Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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Virtual lifeline: online groups aim to ease pandemic anxiety for young cancer survivors
Symptom relief TerminatedThis study tested an online support group designed to help young adults who have finished cancer treatment cope with anxiety and depression during the COVID-19 pandemic. Researchers wanted to see if teaching healthy coping skills through virtual meetings could improve participant…
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated Mar 27, 2026 12:41 UTC
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Tourniquet therapy tested for speedy shoulder recovery
Symptom relief TerminatedThis study aimed to see if a therapy called blood flow restriction (BFR) could help people recover faster from a recent shoulder injury. BFR involves wearing a special pressurized cuff on the arm during light rehab exercises to try and prevent muscle loss. The trial was very smal…
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated Mar 27, 2026 12:38 UTC
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Zapping knee pain: could a temporary nerve device offer relief?
Symptom relief TerminatedThis study tested whether a temporary nerve stimulation device could help people with chronic knee pain from osteoarthritis. The device was meant to block pain signals from the knee. Researchers measured changes in pain levels, quality of life, and medication use in a small group…
Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated Mar 23, 2026 15:17 UTC
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Brain tumor sleep study halted early
Symptom relief TerminatedThis study tested whether a drug called solriamfetol, which promotes wakefulness, could help adults with stable brain tumors (gliomas) feel less sleepy and fatigued, and improve their memory and quality of life. The main goal was to check the drug's safety at different doses. The…
Phase: PHASE2 • Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated Mar 20, 2026 14:48 UTC
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Tiny trial tests if surgery patients can wear sugar sensors
Knowledge-focused TerminatedThis small, ended pilot study tested if a wearable blood sugar monitor (CGM) could be used for patients with diabetes before, during, and after surgery. It aimed to see if the monitors were practical to use in the hospital and if their readings were accurate compared to standard …
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC
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Brain hormone tested as potential pain blocker
Knowledge-focused TerminatedThis study aimed to understand if the hormone oxytocin, given through an IV, could reduce pain. Researchers tested this by applying a mild, heated probe to the skin of healthy volunteers and people with severe knee arthritis, asking them to rate their pain. The goal was to create…
Phase: PHASE2 • Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:37 UTC
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Pilot program aims to smooth the road for cancer survivors
Knowledge-focused TerminatedThis small pilot study tested a new support program called SHAREDCare for people who have finished treatment for lung cancer. The goal was to see if working with a care navigator to create a personalized plan could help survivors better manage their ongoing health and social need…
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:14 UTC