Wake Forest University Health Sciences

This study aimed to see if adding electromagnetic fields to the drug regorafenib could help people with advanced liver cancer live longer without their cancer growing. Only 2 people joined before the study was stopped early. The treatment was for patients who had already tried ot…

This early-stage study tested whether combining precise radiation to the spine with the immunotherapy drug pembrolizumab is feasible for people with advanced spinal tumors pressing on the spinal cord. Only one person enrolled before the study was stopped early. The goal was to se…

This study compared two biologic meshes (Fortiva and Strattice) used to repair ventral hernias. Researchers wanted to see which mesh led to fewer hernias coming back and fewer complications. The study was stopped early and only included 6 adults needing hernia surgery.

This early-phase study tested the safety and best dose of two chemotherapy drugs (gemcitabine and docetaxel) given together with radiation before surgery for adults with large, high-grade soft tissue sarcoma of the arms or legs. Only 9 people took part before the study was stoppe…

This study tested an online support group for young adults (ages 18-39) who had cancer treatment and were feeling anxious or distressed during the COVID-19 pandemic. The goal was to see if teaching healthy coping skills through a virtual group could improve their mood and confide…

This small study tested a spinal cord stimulator (BurstDR SCS) to treat painful diabetic neuropathy in 6 adults whose pain did not respond to standard medications. The goal was to see if the device could reduce leg pain by at least half. The study was terminated early, so results…

This study tested a drug called solriamfetol to see if it could help people with brain tumors (gliomas) feel more awake and improve their memory, mood, and quality of life. Only 2 people enrolled before the study was stopped early. The main goal was to check for side effects.

This study tested a temporary device that stimulates nerves around the knee to relieve chronic pain from osteoarthritis. Twelve adults with knee pain received the treatment, and researchers measured changes in pain intensity and quality of life. The goal was to see if this non-su…

This study looked at a different way to close surgical cuts (incisions) in the belly after gynecologic surgery. Instead of leaving the wound open or closing it all at once, doctors partially closed it right after surgery and fully closed it 4-7 days later. The goal was to see if …

This study looked at whether blood flow restriction therapy could help people regain shoulder muscle strength after an injury. The therapy uses a cuff to partially restrict blood flow during light exercise, aiming to build muscle without heavy weights. Only 3 people took part bef…

This pilot study tested whether continuous glucose monitors (CGMs) could be used in preoperative clinics to help manage blood sugar in people with diabetes before surgery. Researchers placed CGMs on 22 adults during their preoperative visit and tracked accuracy compared to standa…

This pilot study tested a program called SHAREDCare, which helps lung cancer survivors and a navigator work together to address their needs after treatment. The study planned to enroll adults with stage I-IV lung cancer diagnosed within the past two years. However, the study was …

This study looked at whether the antifungal drug ketoconazole could block a protein called tGLI1 in brain tumors. It included 15 adults with breast cancer that spread to the brain or with a type of brain tumor called glioma. The goal was to see if the drug could affect the tumor'…

This study looked at whether oxytocin, a natural hormone, can reduce pain when given through an IV. It included 7 people—some healthy and some with severe knee arthritis. Researchers measured pain from a heated skin patch to see how oxytocin changes pain perception.

This study aimed to measure normal brain blood flow patterns in people using mechanical heart pumps (like LVADs or ECMO). Researchers wanted to find target ranges to help doctors adjust pump settings and avoid brain injuries. The study was terminated early after enrolling only 6 …