New combo therapy for aggressive sarcoma shows early safety data

NCT ID NCT04037527

First seen Nov 01, 2025 · Last updated May 05, 2026 · Updated 36 times

Summary

This early-phase study tested the safety and best dose of two chemotherapy drugs (gemcitabine and docetaxel) given together with radiation before surgery for adults with large, high-grade soft tissue sarcoma of the arms or legs. Only 9 people took part before the study was stopped. The goal was to find the highest safe dose and track side effects, not to cure the disease.

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Contacts and locations

Locations

  • Wake Forest Baptist Comprehensive Cancer Center

    Winston-Salem, North Carolina, 27157, United States

Conditions

Explore the condition pages connected to this study.