Uppsala University
Clinical trials sponsored by Uppsala University, explained in plain language.
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Experimental cell treatment shows promise for COVID-19 lung failure
Disease control CompletedThis early-stage study tested a single dose of mesenchymal stromal cells in 7 COVID-19 patients with severe acute respiratory distress syndrome (ARDS) who were on ventilators. The main goal was to check safety, looking for serious side effects like heart problems or blood clots w…
Phase: PHASE1 • Sponsor: Uppsala University • Aim: Disease control
Last updated Jun 22, 2026 12:05 UTC
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Gentle vein harvesting may keep heart bypasses open longer
Disease control CompletedThis study tested whether a special 'no-touch' method of removing leg veins for heart bypass surgery helps the grafts stay open longer. About 900 people having their first bypass surgery took part. The researchers compared the no-touch technique to the usual method to see which l…
Phase: NA • Sponsor: Uppsala University • Aim: Disease control
Last updated Jun 18, 2026 11:49 UTC
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Diabetes drug showdown: which works better for Early-Stage patients?
Disease control CompletedThis study compared two diabetes medications, dapagliflozin and metformin, in over 2,000 people with early type 2 diabetes. The goal was to see which drug better prevents serious complications like heart attacks, strokes, kidney disease, and eye problems. Participants were follow…
Phase: PHASE4 • Sponsor: Uppsala University • Aim: Disease control
Last updated Jun 10, 2026 13:27 UTC
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New hip cup design aims to stop common complication in elderly fracture patients
Disease control CompletedThis study tested whether a special type of hip implant (dual mobility cup) can prevent the hip from popping out of place after a total hip replacement for a broken hip. The trial involved 1,600 elderly patients with a specific type of hip fracture. Researchers compared the dual …
Phase: NA • Sponsor: Uppsala University • Aim: Disease control
Last updated Jun 08, 2026 13:12 UTC
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Paws in the classroom: dogs may boost school attendance for struggling kids
Symptom relief CompletedThis study tested whether trained social working dogs could help children with problematic school absence. 64 children from grades 3-9 who missed at least 15% of school were randomly assigned to receive either dog-assisted support or support from a special education teacher for 3…
Phase: NA • Sponsor: Uppsala University • Aim: Symptom relief
Last updated Jun 23, 2026 11:55 UTC
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New digital therapy shows promise for burnout recovery
Symptom relief CompletedThis study tested a new online treatment program for people exhausted from long-term stress. 26 participants used a digital therapy that combines education, coping skills, and support. The goal was to see if the program could reduce symptoms of exhaustion and improve well-being.
Sponsor: Uppsala University • Aim: Symptom relief
Last updated Jun 18, 2026 11:51 UTC
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New study tracks Real-Life CPR breathing techniques
Knowledge-focused CompletedThis study observed how emergency medical teams give breaths to adults suffering cardiac arrest outside the hospital. Using a portable device, researchers measured the volume, frequency, and pressure of ventilations during CPR. The goal was to describe current practices, not to t…
Sponsor: Uppsala University • Aim: Knowledge-focused
Last updated Jun 23, 2026 23:35 UTC
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New wearable capnograph could revolutionize ambulance monitoring
Knowledge-focused CompletedThis study tested a new wearable capnograph called MARIE in an ambulance setting. The device measures exhaled carbon dioxide and breathing rate. 20 healthy volunteers and 30 patients being transported by ambulance participated. The goal was to see if the device gives reliable rea…
Phase: NA • Sponsor: Uppsala University • Aim: Knowledge-focused
Last updated Jun 23, 2026 11:59 UTC
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Should heart scans be done right away after cardiac arrest? new study investigates
Knowledge-focused CompletedThis study looked at 1,003 people who had a cardiac arrest outside the hospital and were revived. It compared getting a coronary angiogram (an X-ray of the heart's arteries) right away versus waiting three days. The goal was to see if immediate imaging improves survival at 30 day…
Phase: NA • Sponsor: Uppsala University • Aim: Knowledge-focused
Last updated Jun 23, 2026 11:56 UTC
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New study reveals how often kids in swedish ICUs experience delirium
Knowledge-focused CompletedThis study looked at 676 children in Swedish pediatric intensive care units (PICUs) to find out how often delirium occurs and what factors increase the risk. Delirium is a sudden change in mental state causing confusion or trouble paying attention. The researchers used a simple s…
Sponsor: Uppsala University • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:05 UTC
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Cardiac arrest Survivors' brains under the scanner: new study reveals hidden cognitive toll
Knowledge-focused CompletedThis study looks at how a cardiac arrest affects thinking skills and brain activity over the first year. Researchers will use memory and thinking tests along with brain scans (fMRI) in 48 survivors and compare them to healthy people. They also want to see if emotional issues like…
Sponsor: Uppsala University • Aim: Knowledge-focused
Last updated Jun 22, 2026 11:57 UTC
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When is the right time? study explores tracheostomy timing for COVID-19 patients
Knowledge-focused CompletedThis study looked at 4,000 COVID-19 patients in Swedish ICUs to find the best time to perform a tracheostomy—a procedure that creates an opening in the neck to help with breathing. The goal was to see if earlier or later timing affects how many days patients can be off a ventilat…
Sponsor: Uppsala University • Aim: Knowledge-focused
Last updated Jun 18, 2026 11:53 UTC
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Caffeine's brain secrets revealed: panic disorder study uses 7T MRI
Knowledge-focused CompletedThis study looked at how caffeine changes brain activity, anxiety, and decision-making in 42 people—some with panic disorder and some healthy. Participants took either caffeine or a placebo and then performed tasks inside a powerful 7T MRI scanner. The goal was to understand why …
Phase: NA • Sponsor: Uppsala University • Aim: Knowledge-focused
Last updated Jun 18, 2026 11:48 UTC
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Fibromyalgia mystery: do autoantibodies drive pain?
Knowledge-focused CompletedThis study looked at 164 women with fibromyalgia and healthy controls to see if high levels of certain autoantibodies are linked to worse symptoms and changes in the body, like inflammation and nerve damage. Researchers also examined brain chemicals and immune activity in spinal …
Sponsor: Uppsala University • Aim: Knowledge-focused
Last updated Jun 17, 2026 12:08 UTC
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Longer hospital wait before ICU linked to higher death risk in patients over 80
Knowledge-focused CompletedThis study looked at over 315,000 patients aged 80 and older who were admitted to intensive care units (ICUs) in Sweden. Researchers wanted to see if spending more time in a regular hospital ward before being moved to the ICU was linked to a higher chance of dying within 30 days.…
Sponsor: Uppsala University • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:54 UTC
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COVID-19 organ damage: what happens inside the ICU?
Knowledge-focused CompletedThis study looked at 380 adults in the intensive care unit with suspected or confirmed COVID-19. Researchers tracked organ problems like kidney injury and lung failure, and measured survival rates at 30 days and one year. The goal was to learn how COVID-19 causes organ damage, no…
Sponsor: Uppsala University • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:55 UTC
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Chronic pain patients put balance to the test
Knowledge-focused CompletedThis study looked at whether a balance test called the Mini-BESTest is a reliable tool for people with long-term pain. Researchers tested 73 adults with chronic non-cancer pain and also interviewed some about their balance experiences. The goal was to understand how well the test…
Sponsor: Uppsala University • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:04 UTC
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Could shorter ADHD tests be just as good? new study investigates
Knowledge-focused CompletedThis study looked at 142 children (ages 8-17) referred for ADHD assessment to see if a shorter evaluation works as well as a longer one. Researchers compared how accurate, reliable, and satisfying each approach was, and also checked costs. The goal is to help doctors and families…
Phase: NA • Sponsor: Uppsala University • Aim: Knowledge-focused
Last updated Jun 11, 2026 11:57 UTC