Uppsala University

This study compares a standardized active surveillance protocol to usual care for men with low-risk prostate cancer. The goal is to see if a clear set of rules for when to start treatment can reduce overtreatment and side effects without increasing the risk of cancer spread. Abou…

This study looks at people with a single broken bone in the middle-to-lower back (thoracolumbar burst fracture) but no nerve damage. It compares two standard treatments: surgery and non-surgical care (like a brace). The goal is to see which approach leads to better daily function…

This study tests whether using a personalized risk score (ABC-score) to guide treatment can lower the chance of stroke or death in people with atrial fibrillation, a common heart rhythm problem. About 3,900 participants were randomly assigned to either receive care guided by this…

This study looks at people with relapsing-remitting multiple sclerosis who switched from the drug MabThera to a similar drug called Rixathon. Researchers want to see if the switch causes any changes in nerve damage, brain lesions, relapses, or disability. The study uses health da…

This study looks at whether a group stress management program called Self-Help Plus (SH+) can improve the mental health of refugee mothers and their preschool children in Uganda. About 725 mothers and their children will take part, with some villages getting the program and other…

This study provides an internet-based cognitive behavioral therapy (CBT) program to 200 university students who have mild symptoms of depression or anxiety. The goal is to reduce those symptoms using a treatment that works for both conditions. Students with severe mental health i…

This study uses brain scans (fMRI) to compare how teenage girls with eating disorders and healthy teens react to pictures of food. Researchers want to find differences in brain activity and structure that might explain why some teens develop anorexia. The goal is to better unders…

This observational study looks at blood lactate levels in 16,000 intensive care patients to see if different thresholds for men, women, and various age groups can better predict death or serious illness, especially in sepsis. Researchers will analyze existing hospital data from S…

This study looks at whether a one-year web-based follow-up program helps people who spent a short time in the intensive care unit (ICU). Half of the 330 participants get the web program, and the other half get no follow-up. The goal is to see if the website improves mental health…