Can a simple monitoring schedule prevent unnecessary prostate cancer treatment?

NCT ID NCT02914873

First seen Jan 24, 2026 · Last updated May 16, 2026 · Updated 15 times

Summary

This study compares a standardized active surveillance protocol to usual care for men with low-risk prostate cancer. The goal is to see if a clear plan for repeat biopsies and treatment triggers can reduce overtreatment and side effects without increasing the risk of cancer spread or death. About 2,000 men with recently diagnosed, low-risk prostate cancer are taking part.

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Contacts and locations

Locations

  • Akademiska University Hospital

    Uppsala, Sweden

  • Bedford Hospital

    Bedford, United Kingdom

  • Croydon University Hospital

    Croydon, United Kingdom

  • Epsom and St Helier Hospital

    London, United Kingdom

  • Guy's Hospital

    London, United Kingdom

  • Helsinki University Hospital

    Helsinki, Finland

  • Hospital of Vestfold

    Tønsberg, Norway

  • Linköping University Hospital

    Linköping, Sweden

  • Odense University Hospital

    Odense, Denmark

  • Oslo University Hospital

    Oslo, Norway

  • Queen Elisabeth Hospital

    London, United Kingdom

  • Rigshospitalet

    Copenhagen, Denmark

  • Royal Marsden Hospital

    London, United Kingdom

  • Sahlgrenska University Hospital

    Gothenburg, Sweden

  • Seinäjoki Central Hospital

    Tampere, Finland

  • St Olavs University Hospital

    Trondheim, Norway

  • Sunderby Regional Hospital

    Luleå, Sweden

  • Sundsvall Regional Hospital

    Sundsvall, Sweden

  • Umeå University Hospital

    Umeå, Sweden

  • University Hospital of North Norway

    Tromsø, Norway

  • Växjö Hospital

    Vaxjo, Sweden

  • Ålesund Regional Hospital

    Ålesund, Norway

  • Örebro University Hospital

    Örebro, Sweden

Conditions

Explore the condition pages connected to this study.