University Of Southern California
Clinical trials sponsored by University Of Southern California, explained in plain language.
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Experimental cancer shot trial halted after just two patients
Disease control TerminatedThis early-stage trial tested a combination of two immune-boosting drugs (CMP-001 and INCAGN01949) injected directly into tumors of people with stage IV pancreatic cancer or other advanced solid tumors (excluding melanoma). The goal was to see if the drugs could shrink tumors or …
Phase: PHASE1, PHASE2 • Sponsor: University of Southern California • Aim: Disease control
Last updated Jun 09, 2026 12:10 UTC
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Can MRI and mammography help avoid repeat surgery in breast cancer?
Disease control TerminatedThis study looked at using mammography and breast MRI to find the best candidates for a type of radiation given during surgery (IORT) for early breast cancer. The goal was to see if this approach could reduce the need for additional surgery or radiation. The study was stopped ear…
Phase: NA • Sponsor: University of Southern California • Aim: Disease control
Last updated Jun 08, 2026 13:09 UTC
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Bladder cancer drug combo tested, but study stopped early
Disease control TerminatedThis study tested a combination of two drugs, docetaxel and lapatinib, in people with advanced bladder cancer that had already been treated with chemotherapy. The goal was to see if the combination could stop the cancer from growing longer. The study was stopped early after enrol…
Phase: PHASE2 • Sponsor: University of Southern California • Aim: Disease control
Last updated Jun 08, 2026 13:07 UTC
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Promising combo for tough prostate cancer falls short in early trial
Disease control TerminatedThis study tested a combination of two drugs, bortezomib and docetaxel, in 15 men with advanced prostate cancer that no longer responded to hormone therapy. The goal was to see if the combo could lower PSA levels and ease pain. The trial was stopped early, so results are limited,…
Phase: PHASE2 • Sponsor: University of Southern California • Aim: Disease control
Last updated Jun 01, 2026 18:04 UTC
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Exercise program targets metabolic risks in cancer survivors
Disease control TerminatedThis study looked at whether a specific type of exercise, combining aerobic and resistance training in short bursts, could improve metabolic health in overweight or obese breast and prostate cancer survivors who had finished treatment. The goal was to reduce insulin resistance an…
Phase: NA • Sponsor: University of Southern California • Aim: Disease control
Last updated Jun 01, 2026 17:54 UTC
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Kidney transplant patients may get simpler drug routine
Disease control TerminatedThis study tested whether a once-daily anti-rejection drug (EnvarsusXR) combined with azathioprine works as well as the standard twice-daily drug combo after a kidney transplant. The goal was to prevent organ rejection while keeping the kidney working and the patient alive. The s…
Phase: PHASE4 • Sponsor: University of Southern California • Aim: Disease control
Last updated Jun 01, 2026 17:53 UTC
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Blood test may spot lung cancer without needles in the lungs
Diagnosis TerminatedThis study looked at whether a blood test, called a fluid biopsy, could help diagnose lung cancer. Researchers collected blood samples from 51 people who were either scheduled for a lung biopsy or had recently had one. The goal was to see if the blood test could accurately detect…
Sponsor: University of Southern California • Aim: Diagnosis
Last updated Jun 08, 2026 13:07 UTC
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Bringing comfort home: palliative care study aims to ease suffering
Symptom relief TerminatedThis study tested whether providing palliative care at home, through primary care clinics, helps seriously ill patients with cancer, heart failure, or COPD feel better. Researchers planned to enroll over 1,100 patients and their caregivers, but the study was stopped early. The go…
Phase: NA • Sponsor: University of Southern California • Aim: Symptom relief
Last updated Jun 05, 2026 12:06 UTC
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Sleep aid vs. antipsychotic: which works better for ICU delirium?
Symptom relief TerminatedThis small pilot study looked at two medications, trazodone and quetiapine, to treat delirium (sudden confusion) in adult ICU patients. The goal was to see which drug might shorten confusion, improve sleep, and reduce hospital stays. The study was stopped early with only 10 parti…
Sponsor: University of Southern California • Aim: Symptom relief
Last updated Jun 03, 2026 12:05 UTC
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Tiny trial tests smarter chemo delivery in head and neck cancer
Knowledge-focused TerminatedThis very early study looked at how a new version of the chemotherapy drug paclitaxel (called FID-007) affects immune cells around head and neck tumors. The drug is wrapped in a special polymer to help it reach deeper into tumors while sparing healthy cells. Only 1 person enrolle…
Phase: PHASE1 • Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:05 UTC