University Of Southern California

This early-phase study tests two drugs together—guadecitabine and durvalumab—in people with advanced liver, pancreatic, bile duct, or gallbladder cancers that have spread. The goal is to find the safest dose and see if the combination can shrink tumors. About 55 adults with these…

This study tests whether giving the immunotherapy drug cemiplimab before surgery can help shrink high-risk skin cancers that haven't spread far. About 35 adults with certain types of squamous cell skin cancer will receive the drug and then have surgery. The goal is to see if this…

This study looks at whether eating a low-calorie diet before chemotherapy can lessen side effects like fatigue, nausea, and mouth sores, and also help the chemo work better. About 130 people with breast or prostate cancer are taking part. The goal is to see if a simple diet chang…

This study looks at whether using virtual reality (VR) can lower pain and anxiety in cancer patients who need a bone marrow biopsy or lumbar puncture. About 60 participants will use VR during the procedure and report their pain and anxiety levels. The goal is to see if this simpl…

This study uses a very powerful 7 Tesla MRI scanner to take detailed pictures of the brain in testicular cancer patients who have low testosterone (hypogonadism) and are receiving testosterone replacement therapy. The goal is to see if this advanced imaging can detect changes in …

This study planned to test a special vacuum dressing on surgical wounds after lower leg amputation. It aimed to see if the dressing reduced swelling, helped people walk sooner, and was more comfortable than standard bandages. The study was withdrawn before any participants were e…

This study looks at whether music lessons can improve brain development in children ages 6 to 8. About 114 kids from Los Angeles will be randomly placed in either a music program or an after-school arts program for 24 months. Researchers will use brain scans and behavior tests to…

This study looks at whether a risk assessment screening and a short caregiver training can help prevent elder abuse in people with dementia. About 1,000 caregivers will fill out surveys and some will receive the screening or training. The goal is to see if these tools reduce care…