New combo therapy aims to boost immune attack on kidney cancer

NCT ID NCT03092856

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether adding an experimental drug (PF-04518600) that boosts the immune system to the standard drug axitinib can help control advanced kidney cancer better than axitinib alone. About 62 adults whose cancer has spread and who have already tried an immune checkpoint inhibitor will take part. The main goal is to see if the combination delays cancer growth.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

nonpapillary renal cell carcinoma renal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center

    Cleveland, Ohio, 44195, United States

  • Los Angeles County-USC Medical Center

    Los Angeles, California, 90033, United States

  • USC / Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

  • USC Norris Oncology/Hematology-Newport Beach

    Newport Beach, California, 92663, United States

  • University of California Davis Comprehensive Cancer Center

    Sacramento, California, 95817, United States

  • University of Kansas Cancer Center

    Kansas City, Kansas, 66160, United States

  • University of Pittsburgh Cancer Institute (UPCI)

    Pittsburgh, Pennsylvania, 15232, United States

  • University of Virginia Cancer Center

    Charlottesville, Virginia, 22903, United States

  • Weill Cornell Medical College, New York- Presbyterian Hospital

    New York, New York, 10065, United States