Could a two-drug combo slow kidney cancer better than one?
NCT ID NCT03092856
First seen Jan 05, 2026 · Last updated May 12, 2026 · Updated 21 times
Summary
This study tests whether adding an experimental immune-boosting drug (anti-OX40 antibody) to the standard targeted therapy axitinib helps control advanced kidney cancer better than axitinib alone. About 62 adults whose cancer worsened after prior immunotherapy will receive either the combination or a placebo plus axitinib. The main goal is to see if the combination delays cancer growth.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center
Cleveland, Ohio, 44195, United States
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Los Angeles County-USC Medical Center
Los Angeles, California, 90033, United States
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
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USC / Norris Comprehensive Cancer Center
Los Angeles, California, 90033, United States
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USC Norris Oncology/Hematology-Newport Beach
Newport Beach, California, 92663, United States
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University of California Davis Comprehensive Cancer Center
Sacramento, California, 95817, United States
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University of Kansas Cancer Center
Kansas City, Kansas, 66160, United States
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University of Pittsburgh Cancer Institute (UPCI)
Pittsburgh, Pennsylvania, 15232, United States
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University of Virginia Cancer Center
Charlottesville, Virginia, 22903, United States
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Weill Cornell Medical College, New York- Presbyterian Hospital
New York, New York, 10065, United States
Conditions
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