Smart bomb for kidney cancer: imaging and radiation combo targets tough tumors
NCT ID NCT07688187
First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time
Summary
This trial tests a two-part approach for advanced clear cell kidney cancer that has stopped responding to standard treatments. First, an imaging injection (PD-32766D) lights up cancer cells that have a specific marker (CA9). If the scan shows the marker is present, participants then receive up to six cycles of a radioactive therapy (PD-32766T) designed to deliver radiation directly to those cancer cells. The study aims to find a safe dose and see whether the treatment can shrink tumors.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- PD-32766D (imaging agent) and PD-32766T (radioactive peptide therapy)
- What this could lead to
- If successful, this could offer a new targeted treatment option for people with advanced kidney cancer who have run out of standard therapies.
- What could go wrong
- This is an early-phase trial with a small number of participants, so the treatment may not prove effective or safe. Radioactive therapy carries risks of side effects like damage to healthy tissues.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Research site
RECRUITINGOmaha, Nebraska, 68130, United States
Contact
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