Can a common antibiotic beat syphilis?

NCT ID NCT05548426

Ongoing Disease control Sponsor: University of Southern California Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether the antibiotic linezolid can effectively treat early syphilis in 24 adults. Participants have primary, secondary, or early latent syphilis, and some also have well-controlled HIV. The main goal is to see if linezolid reduces syphilis infection markers in the blood within 6 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

syphilis Treponema infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SYPHILIS

Contacts and locations

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Locations

Howard Brown Health

Chicago, Illinois, 60613, United States
Open Arms HealthCare Center

Jackson, Mississippi, 39216, United States
Open Door Health

Providence, Rhode Island, 02907, United States
University of Mississippi Medical Center

Jackson, Mississippi, 39216, United States
Wake Forest Baptist Health

Greensboro, North Carolina, 27405, United States