University Of Sao Paulo

This study tests a new treatment for a common type of skin cancer called nodular basal cell carcinoma. The therapy combines light and sound waves to destroy cancer cells in a single visit. About 142 adults with small skin cancers (up to 1 cm) will receive this treatment. The goal…

This study tests a smartphone AI tool called Tia Bete that helps people with type 1 diabetes count carbohydrates and adjust their insulin doses. About 50 children and adults will use the tool for six months to see if it improves blood sugar control and quality of life. The goal i…

This study tests whether a nutrition program based on Brazilian dietary guidelines can reduce heart disease risk in people with bipolar disorder. 88 adults with bipolar disorder will either receive usual care or add 15 dietitian-led sessions over several months. Researchers will …

This study tests whether a natural supplement called inorganic nitrate can safely lower blood pressure in pregnant women with chronic hypertension. About 144 women will receive either the supplement or a placebo from the second trimester onward. The goal is to see if it reduces t…

This study tests a 6-month lifestyle program designed to prevent obesity and eating disorders in transgender and gender-diverse adolescents aged 10-14. Participants are randomly assigned to either the program (group sessions and weekly messages) or standard care. The goal is to i…

This study looks at whether taking creatine supplements while doing supervised weight training for 12 weeks can help men with prostate cancer who are on hormone therapy (ADT) maintain or improve their muscle mass, strength, and physical function. ADT often causes muscle loss and …

This study compares two ways to manage pain after minimally invasive surgery for pectus excavatum (a sunken chest). One method freezes the nerves between the ribs (cryoanalgesia), and the other uses an epidural block. The goal is to see which approach leads to a shorter hospital …

This study looks at whether adding a special light treatment (antimicrobial photodynamic therapy) to standard gum cleaning and tongue scraping can better reduce bad breath in people with type 2 diabetes and gum disease. About 32 adults will receive either standard care or standar…

This study tests whether a single dose of ayahuasca or esketamine can reduce premenstrual symptoms in healthy women. Twenty volunteers will receive one of the two treatments in a double-blind design. The goal is to see if these substances affect the menstrual cycle and related mo…

This study is testing how a single dose of ayahuasca or esketamine affects the way healthy women see their bodies. Twenty volunteers will be randomly assigned to receive one of the two substances. The goal is to understand changes in body image perception, not to treat any condit…

This study tests whether a smartwatch connected to a digital platform can help doctors spot heart rhythm problems like atrial fibrillation early. About 520 adults with heart disease or who recently had a heart procedure will wear a smartwatch and a standard heart monitor. The goa…